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- Testosterone alternative in hypogonadal men with angina improves ischaemic threshold and quality of life.
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Moreover, a element of endothelial dysfunction has been proposed, which may contribute to abnormal vessel reactivity. However, testosterone in physiologic doses might even be helpful in patients with angina , have greater ischemic thresholds and improved high quality of life . Short-term intracoronary administration of testosterone induces coronary artery dilation and will increase coronary blood flow in men with established coronary artery disease . Therefore, an interaction of endogenous elements of the patient’s threat profile as well as the testosterone dosing may be problems with whether or not adverse occasions happen.
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Discussion And Review Of The Literature
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with traditional cardiac danger elements utilizing supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person also had polycythemia, likely secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the best coronary artery. Physicians and sufferers ought to pay consideration to the scientific penalties of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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